Risk genes for schizophrenia and autism conspicuously activate in the same neuronal neighborhood of the brain’s cortex, or outer mantel, during infancy. This suggests some related underlying illness processes – even though known genetic variations associated with the disorders overlap by only 5 percent, say researchers.
Their study, which pinpointed the developmental trajectories of the suspect genes in the monkey brain, also identified divergent timing of risk gene activation that might help to explain the differing courses of the illnesses. Autism-related genes first switched on in newborn neurons during prenatal development, while schizophrenia risk genes didn’t activate until infancy
Related posts:
- Medicare Card, NIH-Funded Brain Atlas Offers Clues to Psychiatric Disorders A comprehensive three-dimensional atlas of the developing human brain that incorporates gene activity along with anatomical reference atlases and neuroimaging data has released its first major report online today in Nature. This National Institutes of Health (NIH)-funded resource, freely available to the public, enables researchers to answer questions related to the early roots of brain-based […]...
- Medicare Card, Gene therapy shows promise for treating Niemann-Pick disease type C1 Medicare Card, Gene therapy shows promise for treating Niemann-Pick disease type C1...
- Balance tips toward environment as heritability ebbs in autism? The largest and most rigorous twin study of its kind to date has found that shared environment influences susceptibility to autism more than previously thought. The study, supported by the National Institutes of Health, found that shared environmental factors — experiences and exposures common to both twin individuals — accounted for 55 percent of strict […]...
- Balance tips toward environment as heritability ebbs in autism? The largest and most rigorous twin study of its kind to date has found that shared environment influences susceptibility to autism more than previously thought. The study, supported by the National Institutes of Health, found that shared environmental factors — experiences and exposures common to both twin individuals — accounted for 55 percent of strict […]...
- Medicare Card, Seven genetic risk factors found to be associated with common eye disorder Medicare Card, Seven genetic risk factors found to be associated with common eye disorder...
- Medicare Card, Different Genes, Same Risk Pathway in Schizophrenia Medicare Card, Different Genes, Same Risk Pathway in Schizophrenia...
- Spontaneous gene glitches linked to autism risk with older dads Researchers have turned up a new clue to the workings of a possible environmental factor in: fathers were four times more likely than mothers to transmit tiny, spontaneous mutations to their children with the disorders. Moreover, the number of such transmitted genetic glitches increased with paternal age. The discovery may help to explain earlier evidence […]...
- Rare gene glitch may hold clues for schizophrenia — NIH-funded study Rare gene glitch may hold clues for schizophrenia -- NIH-funded study...
- Medicare Card, Risk gene for Alzheimer’s disease associated with lower brain amyloid Medicare Card, Risk gene for Alzheimer’s disease associated with lower brain amyloid...
- Medicare Card, Tanning gene linked to increased risk of testicular cancer Medicare Card, Tanning gene linked to increased risk of testicular cancer ...
- Medicare Card, The U.S. Department of the Interior shared. Medicare Card, The U.S. Department of the Interior shared....
- Medicare Card, Autism Awareness Month Autism spectrum disorders (ASDs) are a group of developmental disabilities that can cause social, communication, and behavioral challenges. The Centers for Disease Control and Prevention estimates that about 1 in 88 children in the U.S. has an ASD. While there are no proven cures for autism spectrum disorders, research has shown that early treatment can […]...
- Medicare Card, Autism Progress Dr. Insel highlights key recent findings in research on autism spectrum disorders. Every year the Interagency Autism Coordinating Committee (IACC) updates its Strategic Plan for Autism Spectrum Disorder Research, identifying progress and new opportunities across the range of autism spectrum disorder (ASD) research. Each year this task gets more difficult. In 2012, the speed of […]...
- Medicare Card, Agent reduces autism-like behaviors in mice National Institutes of Health researchers have reversed behaviors in mice resembling two of the three core symptoms of autism spectrum disorders (ASD). An experimental compound, called GRN-529, increased social interactions and lessened repetitive self-grooming behavior in a strain of mice that normally display such autism-like behaviors, the researchers say....
- Medicare Card, Science News » Agent Reduces Autism-like Behaviors in Mice Autism-like behaviors in mice have been reduced, using an experimental agent being tested in patients for a related disorder....