Using a sensitive new technology called single-cell RNA-seq on cells from mice, scientists have created the first high-resolution gene expression map of the newborn mouse inner ear. The findings provide new insightThis link will open a non-federal website in a new window. into how epithelial cells in the inner ear develop and differentiate into specialized cells that serve critical functions for hearing and maintaining balance. Understanding how these important cells form may provide a foundation for the potential development of cell-based therapies for treating hearing loss and balance disorders. The research was conducted by scientists at the National Institute on Deafness and Other Communication Disorders (NIDCD), part of the National Institutes of Health.
Related posts:
- Medicare Card, NIH scientists pursue new therapies to improve rare disease drug development Medicare Card, NIH scientists pursue new therapies to improve rare disease drug development...
- Researchers develop mouse with ‘off switch’ in key brain cell population NIH-funded scientists have developed a strain of mice with a built-in off switch that can selectively shut down the animals’ serotonin-producing cells, which make up a brain network controlling breathing, temperature regulation, and mood. The switch controls only the serotonin-producing cells, and does not affect any other cells in the animal’s brains or bodies....
- Medicare Card, NIH scientists map first steps in flu antibody development Medicare Card, NIH scientists map first steps in flu antibody development...
- Medicare Card, Scientists Identify Markers, Human Breast Cancer Cells, Linked to Development of an Aggressive, But Less Common Form of Breast Cancer Scientists have identified a group of surface markers on cells linked to an aggressive type of breast cancer called estrogen receptor-negative cancer. In this preliminary study, estrogen-negative breast cancer developed when three markers, CD44+, CD49fhi, and CD133hi were present simultaneously on the surface of human cells taken from breast cancer patients and transplanted into a […]...
- Medicare Card, NIH scientists uncover how immune cells sense who they are Medicare Card, NIH scientists uncover how immune cells sense who they are...
- Scientists find approach to enhance and prolong immune attack against tumor cells Investigators have identified a new class of human immune cells that behave like stem cells. These cells, a subtype of T lymphocytes, which comprise a small fraction of white blood cells, may prove more effective than any previously reported type of T cell for treating tumors. The study, by scientists at the National Cancer Institute […]...
- Blueprint empowers drug development for nervous system disorders The National Institutes of Health has made awards to investigators across the United States for an ambitious set of projects seeking to develop new drugs for disorders of the nervous system....
- Medicare Card, NIH study uncovers a starring role for supporting cells in the inner ear Medicare Card, NIH study uncovers a starring role for supporting cells in the inner ear...
- Medicare Card, NIH and Italian scientists develop nasal test for human prion disease Medicare Card, NIH and Italian scientists develop nasal test for human prion disease...
- Medicare Card, NIH scientists find six new genetic risk factors for Parkinson’s Medicare Card, NIH scientists find six new genetic risk factors for Parkinson's...
- Medicare, Study of MicroRNA, Helps NIH Scientists, Unlock Secrets of Immune Cells With the rapid and continuous advances in biotechnology, scientists are better able to see inside the nucleus of a cell to unlock the secrets of its genetic material. However, what happens outside of the nucleus has, in many ways, remained a mystery. Now, researchers with the National Institutes of Health are closer to understanding how […]...
- Medicare, NHLBI to Hold Workshop, Health Consequences of Sickle Cell Trait Scientists from across the nation will gather June 3-4 to discuss what is known about sickle cell trait and the potential health implications related to this genetic blood condition. “Framing the Research Agenda for Sickle Cell Trait” will examine the ethical, legal, social, and public health impacts of the blood condition....
- Medicare Card: Gene Linked to Alzheimer’s Disease Plays Key Role in Cell Survival Scientists have discovered that a gene linked to Alzheimer’s disease may play a beneficial role in cell survival by enabling neurons to clear away toxic proteins. A study funded by the National Institute on Aging (NIA), part of the National Institutes of Health, shows the presenilin 1 (PS1) gene is essential to the function of […]...
- TCGA discovers potential therapeutic targets for lung squamous cell carcinoma Researchers have identified potential therapeutic targets in lung squamous cell carcinoma, the second most common form of lung cancer. The Cancer Genome Atlas (TCGA) Research Network study that appeared online Sept. 9, 2012, and in print Sept. 27, 2012, in the journal Nature, comprehensively characterized the lung squamous cell carcinoma genome. The study found a […]...
- Medicare Card, Adults stop anti-rejection drugs after partial stem-cell transplant reverses sickle cell disease NIH trial success suggests a new treatment option for older, sicker patients. Half of patients in a trial have safely stopped immunosuppressant medication following a modified blood stem-cell transplant for severe sickle cell disease, according to a study in the July 1 issue of the Journal of the American Medical Association External Web Site Policy. […]...