Researchers at the National Institutes of Health have identified a potential new drug that could help in the treatment of a form of Batten disease, a fatal childhood disorder. The researchers tested the drug in mice with the disease and found that it slowed the loss of coordination seen in the disorder, and extended the animals’ life span.

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  1. Researchers identify gene variant in Proteus syndrome A team of researchers has identified the genetic mutation that causes Proteus syndrome, a rare disorder in which tissue and bone grows massively out of proportion. The discovery, which has implications for potential drug therapies and even cancer, appears in the July 27, 2011, early online edition of the New England Journal of Medicine. The […]...
  2. Medicare Mouse study shows effect of blood pressure drug on Alzheimer’s disease A drug used decades ago to treat high blood pressure has been shown to improve learning and memory in mouse models of Alzheimer’s disease, according to a new study by researchers at the National Institute on Aging (NIA), part of the National Institutes of Health. The study found that the drug, diazoxide, acted on nerve […]...
  3. Researchers identify genetic cause of new vascular disease Clinical researchers at the National Institutes of Health’s Undiagnosed Diseases Program (UDP) have identified the genetic cause of a rare and debilitating vascular disorder not previously explained in the medical literature. The adult-onset condition is associated with progressive and painful arterial calcification affecting the lower extremities, yet spares patients’ coronary arteries. The new disease finding […]...
  4. NIH-sponsored research yields promising malaria drug candidate A chemical that rid mice of malaria-causing parasites after a single oral dose may eventually become a new malaria drug if further tests in animals and people uphold the promise of early findings. The compound, NITD609, was developed by an international team of researchers including Elizabeth A. Winzeler, Ph.D., a grantee of the National Institute […]...
  5. Medicare Card: NIH Researchers Identify New Steps in Spread of Malaria Parasite Through Bloodstream Researchers at the National Institutes of Health have observed two previously unknown steps in the spread of the malaria parasite through the bloodstream. And in laboratory cultures, the researchers interfered with one of these steps, raising the possibility that new drug treatments could be developed to combat the disease....
  6. Researchers slow immune attack on ovaries in mice In a study of mice, researchers have slowed an immune system attack on the ovaries. The mice developed a disorder resembling primary ovarian insufficiency (POI), a menopause-like condition that affects women under the age of 40, sometimes years or even decades before normal menopause. The study was conducted by scientists at the National Institutes of […]...
  7. Medicare Card, NIH researchers identify novel genes that may drive rare, aggressive form of uterine cancer Medicare Card, NIH researchers identify novel genes that may drive rare, aggressive form of uterine cancer...
  8. Medicare Card, NIH researchers use brain imaging to understand genetic link between Parkinson’s and a rare disease Medicare Card, NIH researchers use brain imaging to understand genetic link between Parkinson’s and a rare disease...
  9. Gene replacement treats copper deficiency disorder in mice Gene therapy plus an injection of copper dramatically improved survival in mice with a condition that mimics the often fatal childhood disorder Menkes disease, according to a study by researchers at the National Institutes of Health....
  10. Uterine stem cells used to treat diabetes in mice Researchers funded by the National Institutes of Health have converted stem cells from the human endometrium into insulin-producing cells and transplanted them into mice to control the animals’ diabetes....
  11. Therapeutics for Rare and Neglected Diseases Program announces next round of drug development projects Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease....
  12. Researchers Identify Gene Mutations Underlying Risk for Most Common Form of Parkinson’s Disease Parkinson's disease, which affects about 1.5 million Americans, is a progressive neurologic disorder caused by the degeneration of nerve cells in the portion of the brain that controls movement....
  13. Scientists Identify Brain Circuits Related to the Initiation and Termination of Movement Sequences in NIH-Supported Study In humans, throwing a ball, typing on a keyboard, or engaging in most other physical activities involves the coordination of numerous discrete movements that are organized as action sequences. Scientists at the National Institutes of Health and the Gulbenkian Institute in Portugal have identified brain activity in mice that can signal the initiation and termination […]...
  14. Medicare Card, Science News » Agent Reduces Autism-like Behaviors in Mice Autism-like behaviors in mice have been reduced, using an experimental agent being tested in patients for a related disorder....
  15. Medicare: Researchers identify key proteins of inner ear transduction channel National Institutes of Health-funded researchers have identified two proteins that may be the key components of the long-sought after mechanotransduction channel in the inner ear — the place where the mechanical stimulation of sound waves is transformed into electrical signals that the brain recognizes as sound....