Findings linking two biological mechanisms known to play a role in mental illness demonstrate how unrelated genes can work through effects on a common pathway. Many genes contribute to risk of schizophrenia; this work helps illuminate this complex pathway, a potential target for development of future medications.
Related posts:
- Rare gene glitch may hold clues for schizophrenia — NIH-funded study Rare gene glitch may hold clues for schizophrenia -- NIH-funded study...
- MedicareCard.com – Scientists Find Genes That Influence Brain Wave Patterns Scientists have identified new genes and pathways that influence an individual’s typical pattern of brain electrical activity, a trait that may serve as a useful surrogate marker for more genetically complex traits and diseases. One of the genes, for example, was found to be associated with alcoholism....
- Medicare: Same Genes Suspected in Both Depression and Bipolar Illness Researchers, for the first time, have pinpointed a genetic hotspot that confers risk for both bipolar disorder and depression. People with either of these mood disorders were significantly more likely to have risk versions of genes at this site than healthy controls...
- Medicare, Gene regulator in brain’s executive hub tracked across lifespan For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select […]...
- NIH Genomic Mapping Study Finds Largest Set of Genes Related to Major Risk Factor for Heart Disease Scanning the genomes of more than 100,000 people from all over the world, scientists report the largest set of genes discovered underlying high cholesterol and high triglycerides — the major risk factors for coronary heart disease, the nation’s number one killer. Taken together, the gene variants explain between a quarter and a third of the […]...
- Additional Genes Associated with Age-Related Macular Degeneration Identified Additional Genes Associated with Age-Related Macular Degeneration Identified...
- Genes that Protect Chromosome Tips May Boost Longevity Genes that Protect Chromosome Tips May Boost Longevity...
- Medicare, Researchers discover 71 new human genes associated with bowel diseases Researchers have found 71 new human genes associated with Crohn’s disease and ulcerative colitis, two chronic inflammatory bowel diseases (IBD) that affect the small and large (colon) intestines of nearly 2.5 million people worldwide. This study brings the total number of known genes associated with IBD to 163....
- NIH-supported mouse studies suggest treatment target for alcohol problems A molecular pathway within the brain’s reward circuitry appears to contribute to alcohol abuse, according to laboratory mouse research supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health (NIH). The findings, published online today in Proceedings of the National Academy of Sciences, also provide evidence that […]...
- Science News: Gene Regulator in Brain’s Execusive Hub Tracked Across Lifespan For the first time, scientists have tracked the activity, across the lifespan, of an environmentally responsive regulatory mechanism that turns genes on and off in the brain’s executive hub. Among key findings of the study by National Institutes of Health scientists: genes implicated in schizophrenia and autism turn out to be members of a select […]...
- MedicareCard.com – Adding Coronary Calcium Score to Traditional Risk Factors Improves Risk Assessment for Heart Disease Including a coronary artery calcium score in a risk assessment for future heart disease events, such as heart attacks, provides a better estimate in some populations than a standard coronar...
- Medicare Research, Songbird Genome Analysis, Reveals New Insights Into Vocal Behavior An international research consortium has identified more than 800 genes that appear to play a role in the male zebra finch's ability to learn elaborate songs from his father. The researchers also found evidence that song behavior engages complex gene regulatory networks within the brain of the songbird -- networks that rely on parts of the genome once considered junk....
- Medicare, Medicare Card, NIH and Wellcome Trust Announce Partnership To Support Population-based Genome Studies in Africa The National Institutes of Health, an agency of the U.S. Department of Health and Human Services, and the Wellcome Trust, a global charity based in London, today announced a partnership to support population-based genetic studies in Africa of common, non-communicable disorders such as heart disease and cancer, as well as communicable diseases such as malaria. […]...
- Medicare Card, Non-profits sign research and development agreement The National Institutes of Health today announced an agreement with two non-profit organizations to accelerate the development of potential clinical therapies for rare blood cancers....
- Investigators discover new mechanism that may be important for learning and memory New findings in mice suggest that the timing when the neurotransmitter acetylcholine is released in the brain’s hippocampus may play a key role in regulating the strength of nerve cell connections, called synapses. Understanding the complex nature of neuronal signaling at synapses could lead to better understanding of learning and memory, and novel treatments for […]...