Genetic abnormality predicts benefit from treatment for a rare brain tumor

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1. The Most Common Form of Brain Cancer in Adults The most common form of malignant brain cancer in adults, glioblastoma multiforme (GBM), has 4 distinct molecular subtypes, according to a new study. The finding may lead to more personalized approaches to treating GBM patients....
2. Medicare, Deep Brain Stimulation, Two Different Targets, Produces Similar Motor Improvements in Parkinson’s Disease In a major study, investigators have compared how individuals with Parkinson’s disease respond to deep brain stimulation (DBS) at two different sites in the brain. Contrary to current belief, patients who received DBS at either site in the brain experienced comparable benefits for the motor symptoms of Parkinson’s....
3. Medicare: Researchers produce detailed map of gene activity in mouse brain A new atlas of gene expression in the mouse brain provides insight into how genes work in the outer part of the brain called the cerebral cortex. In humans, the cerebral cortex is the largest part of the brain, and the region responsible for memory, sensory perception and language....
4. Researchers trace early journey of modulating cells in brain Key cells in the brain region known as the hippocampus are formed in the base of the brain late in fetal life and undertake a long journey before reaching their final destination in the center of the brain shortly after birth, according to researchers at the National Institutes of Health....
5. New technique identifies first events in tumor development A novel technique that enables scientists to measure and document tumor-inducing changes in DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas, and could potentially lead to the discovery of ways to stop those events....
6. Rare gene glitch may hold clues for schizophrenia — NIH-funded study Rare gene glitch may hold clues for schizophrenia -- NIH-funded study...
7. Researchers extend use of gene therapy to treat a soft tissue tumor Researchers extend use of gene therapy to treat a soft tissue tumor...
8. Brain electrical activity spurs insulation of brain’s wiring Researchers at the National Institutes of Health have discovered in mice a molecular trigger that initiates myelination, the process by which brain cell networks are reinforced with an insulating material called myelin that speeds their ability to transmit messages....
9. Funded study shows reduction in death for men with intermediate-grade prostate cancer Short-term hormone therapy given in combination with radiation therapy to men with early-stage prostate cancer increased their chances of living longer compared to treatment with radiation therapy alone, according to a clinical trial supported by the National Cancer Institute (NCI), part of the National Institutes of Health. Benefits of the combined treatment were limited mainly […]...
10. Scientists find approach to enhance and prolong immune attack against tumor cells Investigators have identified a new class of human immune cells that behave like stem cells. These cells, a subtype of T lymphocytes, which comprise a small fraction of white blood cells, may prove more effective than any previously reported type of T cell for treating tumors. The study, by scientists at the National Cancer Institute […]...
11. Medicare – Targeting the Blood-Brain Barrier, May Delay Progression of Alzheimer’s Disease Researchers may be one step closer to slowing the onset and progression of Alzheimer's disease. An animal study supported by the National Institute of Environmental Health Sciences (NIEHS), ...
12. Therapeutics for Rare and Neglected Diseases Program announces next round of drug development projects Researchers will begin drug development projects for rare and neglected diseases that include potential treatments for a musculoskeletal disorder, a cognitive dysfunction disorder, a virus that affects the central nervous system of newborns, a parasitic worm infection, a form of muscular dystrophy and a rare lung disease....
13. Down syndrome consortium formed National Institutes of Health has joined with organizations interested in Down syndrome to form a consortium that will foster the exchange of information on biomedical and biobehavioral research on the chromosomal condition....
14. Medicare, After 40 Years, NIH-Supported Researchers Identify Possible New Treatment for Severe Vasculitis Investigators have made a major advance in treating people with a severe form of vasculitis, anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, a rare but devastating disease of blood vessels. In a six-month study, a new treatment strategy provided the same benefits as the current standard of care used for more than 40 years but required less […]...
15. Summit to focus on management of radiation dose in computerized tomography Members of the media are invited to attend a National Institutes of Health conference focused on transforming computed tomography (CT) technology and its use to achieve minimal public health risks from radiation exposure. A specific goal of this conference is to identify the technological steps and associated research required to reduce the radiation dose from […]...