A multinational research team led by scientists at the National Institutes of Health has found that a genetic variant of a brain receptor molecule may contribute to violently impulsive behavior when people who carry it are under the influence of alcohol. A report of the findings, which include human genetic analyses and gene knockout studies in animals, appears in the Dec. 23 issue of Nature.

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  1. Medicare, Medicare Card, Receptor Variant Influences, Dopamine Response to Alcohol A genetic variant of a receptor in the brain’s reward circuitry plays an important role in determining whether the neurotransmitter dopamine is released in the brain following alcohol intake, according to a study led by researchers at the National Institute on Alcohol Abuse and Alcoholism (NIAAA), part of the National Institutes of Health. Dopamine is […]...
  2. USU study maps hotspots of genetic rearrangement Researchers have zoomed in on mouse chromosomes to map hotspots of genetic recombination — sites where DNA breaks and reforms to shuffle genes. The findings of the scientists at the National Institutes of Health and Uniformed Services University of Health Sciences (USU) have the potential to improve the detection of genes linked to disease and […]...
  3. Medicare, NIH-Supported Study, Looks for Earliest Changes, in the Brain That May Lead to Alzheimer’s Disease Volunteers are being sought for a clinical study examining the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer’s disease appear. Researchers are looking for people with the very earliest complaints of memory problems that affect their daily activities. The study will follow participants over […]...
  4. Genetic Testing Registry (GTR) Will This Help Medicare The National Institutes of Health announced today that it is creating a public database that researchers, consumers, health care providers, and others can search for information submitted voluntarily by genetic test providers. The Genetic Testing Registry (GTR) aims to enhance access to information about the availability, validity, and usefulness of genetic tests....
  5. Medicare, Gene Variant that may Prevent African Sleeping Sickness also Leads to Increased Chance of Kidney Disease National Institutes of Health researchers and grantees have found that gene variants in APOL1, more common in African Americans, come with both health risk and reward, as reported in the July 15 online issue of Science....
  6. Medicare, Medicare Card, NIH and Wellcome Trust Announce Partnership To Support Population-based Genome Studies in Africa The National Institutes of Health, an agency of the U.S. Department of Health and Human Services, and the Wellcome Trust, a global charity based in London, today announced a partnership to support population-based genetic studies in Africa of common, non-communicable disorders such as heart disease and cancer, as well as communicable diseases such as malaria. […]...
  7. Medicare, After 40 Years, NIH-Supported Researchers Identify Possible New Treatment for Severe Vasculitis Investigators have made a major advance in treating people with a severe form of vasculitis, anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis, a rare but devastating disease of blood vessels. In a six-month study, a new treatment strategy provided the same benefits as the current standard of care used for more than 40 years but required less […]...
  8. Medicare, NIH researchers identify genetic elements influencing the risk of type 2 diabetes Medicare, NIH researchers identify genetic elements influencing the risk of type 2 diabetes: A team led by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, has captured the most comprehensive snapshot to date of DNA regions that regulate genes in human pancreatic islet cells, a subset of […]...
  9. Third generation map of human genetic variation published An international consortium today published a third-generation map of human genetic variation, called the HapMap, which includes data from an additional seven global populations, increasing the total number to 11 populations. The improved resolution will help researchers interpret current genome studies aimed at finding common and rarer genetic variants associated with complex diseases. Find good […]...
  10. Genetic mutation linked to inherited forms of ALS, dementia National Institutes of Health scientists and worldwide teams of researchers have identified the most common genetic cause known to date for two neurological diseases, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The discovery offers clues to underlying mechanisms of these diseases, and may eventually contribute to the design and testing of possible therapies....
  11. Medicare, Study of MicroRNA, Helps NIH Scientists, Unlock Secrets of Immune Cells With the rapid and continuous advances in biotechnology, scientists are better able to see inside the nucleus of a cell to unlock the secrets of its genetic material. However, what happens outside of the nucleus has, in many ways, remained a mystery. Now, researchers with the National Institutes of Health are closer to understanding how […]...
  12. Researchers identify genetic cause of new vascular disease Clinical researchers at the National Institutes of Health’s Undiagnosed Diseases Program (UDP) have identified the genetic cause of a rare and debilitating vascular disorder not previously explained in the medical literature. The adult-onset condition is associated with progressive and painful arterial calcification affecting the lower extremities, yet spares patients’ coronary arteries. The new disease finding […]...
  13. Study identifies gene that suppresses cell’s immune activation A new study of prostate tumors has shown that a gene, FOXO3, suppresses activation of cells related to immunity and thus leads to a reduced immune response against a growing cancer. One of the main problems in treating cancer by vaccine or immunotherapy is that tumors often evade the body’s immune response — and one […]...
  14. Study finds stroke risk factors may lead to cognitive problems High blood pressure and other known risk factors for stroke also increase the risk of developing cognitive problems, even among people who have never had a stroke, a study funded by the National Institutes of Health has found....
  15. Medicare, Scientists reveal how biological activity is regulated in fruit fly and roundworm genomes Scientists today published catalogs of the fruit fly and roundworm’s functional genomic elements: DNA sequences in the genome that carry the instructions and determine which genes are turned on and off at various times in different cells....