Small genetic differences between individuals help explain why some people have a higher risk than others for developing illnesses such as diabetes or cancer. Today in the journal Nature, the 1000 Genomes Project, an international public-private consortium, published the most comprehensive map of these genetic differences, called variations, estimated to contain approximately 95 percent of the genetic variation of any person on Earth.

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  1. MedicarCard.com, NIH, Human Microbiome Project, Researchers Publish First Genomic, Collection of Human Microbes The Human Microbiome Project (HMP) today published an analysis of 178 genomes from microbes that live in or on the human body. The researchers discovered novel genes and proteins that serve functions in human health and disease, adding a new level of understanding to what is known about the complexity and diversity of these organisms....
  2. Third generation map of human genetic variation published An international consortium today published a third-generation map of human genetic variation, called the HapMap, which includes data from an additional seven global populations, increasing the total number to 11 populations. The improved resolution will help researchers interpret current genome studies aimed at finding common and rarer genetic variants associated with complex diseases. Find good […]...
  3. Medicare, NIH launches Genotype-Tissue Expression project The National Institutes of Health today announced awards to support an initiative to understand how genetic variation may control gene activity and its relationship to disease. Launched as a pilot phase, the Genotype-Tissue Expression (GTEx) project will create a resource researchers can use to study inherited susceptibility to illness and will establish a tissue bank […]...
  4. Medicare Research, Songbird Genome Analysis, Reveals New Insights Into Vocal Behavior An international research consortium has identified more than 800 genes that appear to play a role in the male zebra finch's ability to learn elaborate songs from his father. The researchers also found evidence that song behavior engages complex gene regulatory networks within the brain of the songbird -- networks that rely on parts of the genome once considered junk....
  5. The Cancer Genome Atlas completes detailed ovarian cancer analysis An analysis of genomic changes in ovarian cancer has provided the most comprehensive and integrated view of cancer genes for any cancer type to date. Ovarian serous adenocarcinoma tumors from 500 patients were examined by The Cancer Genome Atlas (TCGA) Research Network and analyses are reported in the June 30, 2011, issue of Nature. MedicareCard.com […]...
  6. Origins of XMRV deciphered, undermining claims for a role in human disease Delineation of the origin of the retrovirus known as XMRV from the genomes of laboratory mice indicates that the virus is unlikely to be responsible for either prostate cancer or chronic fatigue syndrome in humans, as has been widely published. The virus arose because of genetic recombination of two mouse viruses. Subsequent infection of lab […]...
  7. In NIH-funded study, researchers uncover early step in the cascade of brain events leading up to addiction A regulatory protein best known for its role in a rare genetic brain disorder also may play a critical role in cocaine addiction, according to a recent study in rats, funded by the National Institute on Drug Abuse (NIDA), a component of the National Institutes of Health. The study was published today in the journal […]...
  8. Medicare, Scientists reveal how biological activity is regulated in fruit fly and roundworm genomes Scientists today published catalogs of the fruit fly and roundworm’s functional genomic elements: DNA sequences in the genome that carry the instructions and determine which genes are turned on and off at various times in different cells....
  9. Medicare, Alzheimer’s Disease Neuroimaging Initiative enters next phase of research The National Institutes of Health is expanding the Alzheimer’s Disease Neuroimaging Initiative (ADNI), a groundbreaking study that will recruit hundreds of new volunteers to help define the subtle changes that may take place in the brains of older people many years before overt symptoms of Alzheimer’s disease appear. ADNI is the largest public-private partnership to […]...
  10. Medicare, NHGRI charts course for the next phase of genomics research Medicare, NHGRI charts course for the next phase of genomics research...
  11. Medicare, November Is National Diabetes Month Learn more about the symptoms of diabetes and the differences between Type 1 and Type 2 diabetes. Type 2 diabetes is often preventable, so find out what you can do to stay healthy....
  12. Distribution of cancers in the HIV/AIDS population is shifting As treatments for HIV/AIDS improve and patients are living longer, the distribution of cancers in this population has undergone a dramatic shift in the United States. While cases of the types of cancer that have been associated with AIDS progression have decreased, cases of other types of cancer are on the rise. These results, reported […]...
  13. Medicare Future? Pathways that Can Repair Brca1 Cancer Gene Mutation Clarified in Mice In a new study in mice, scientists have compensated for mutations in the Brca1 gene that can lead to cancer by deleting a second gene, which then lessens the probability of cancer. Mice Brca1-associated mammary tumors have significant similarities to human BRCA1- associated (BReast CAncer 1, early onset) breast cancer in regard to tumor aggressiveness, high incidence, mutations and genetic instability. The study, led by scientists at National Cancer Institute (NCI), part of the National Institutes of Health, and their colleagues, appeared online April 1, 2010 and in print April 16, 2010, in the journal Cell....
  14. Researchers identify genetic cause of new vascular disease Clinical researchers at the National Institutes of Health’s Undiagnosed Diseases Program (UDP) have identified the genetic cause of a rare and debilitating vascular disorder not previously explained in the medical literature. The adult-onset condition is associated with progressive and painful arterial calcification affecting the lower extremities, yet spares patients’ coronary arteries. The new disease finding […]...
  15. MedicarCard.com Update – NIH Study Offers Hope to Patients with Nonalcoholic Steatohepatitis A daily dose of a specific form of vitamin E significantly improved the liver disease, nonalcoholic steatohepatitis (NASH), according to a study funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health...