A relatively new method of targeting specific DNA sequences in zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

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  1. Medicare Card, NHGRI to develop revolutionary technologies for exploring genome function The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, has awarded 10 grants, totaling $10.5 million, to develop revolutionary technologies that will help researchers identify millions of genomic elements that play a role in determining what genes are expressed and at what levels in different cells. These multi-year grants are […]...
  2. Discovered gene causes Kabuki syndrome Using a new, rapid and less expensive DNA sequencing strategy, scientists have discovered genetic alterations that account for most cases of Kabuki syndrome, a rare disorder that causes multiple birth defects and mental retardation. Instead of sequencing the entire human genome, the new approach sequences just the exome, the 1-2 percent of the human genome […]...
  3. Medicare Card, NIH funds next step of cutting-edge research into Alzheimer’s disease genome Teams of scientists will use support from the National Institutes of Health to conduct research into the genetic underpinnings of Alzheimer’s disease, analyzing how genome sequences — the order of chemical letters in a cell’s DNA — may contribute to increased risk or protect against the disease. The NIH awarded grants for using innovative new […]...
  4. Medicare Card News: NIH Researchers Explore How Healthy, Young Adults View the Role Genetics Plays in Improving Health Most healthy young adults place greater emphasis on health habits than on genetic risk factors when considering what causes common diseases, a research team from the National Human Genome Research Institute (NHGRI) and the Henry Ford Health System in Detroit has found. The study, based on a survey of 25- to-45-year-olds, was released June 8, […]...
  5. Medicare Card, NIH researchers use brain imaging to understand genetic link between Parkinson’s and a rare disease Medicare Card, NIH researchers use brain imaging to understand genetic link between Parkinson’s and a rare disease...
  6. Medicare Card, NIH launches trial for rare degenerative muscle disease treatment Medicare Card, NIH launches trial for rare degenerative muscle disease treatment...
  7. Medicare Card, Two NIH landmark studies show power of epidemiology research Medicare Card, Two NIH landmark studies show power of epidemiology research ...
  8. Medicare Card, The 1000 Genomes Project more than doubles catalog of human genetic variation Medicare Card, The 1000 Genomes Project more than doubles catalog of human genetic variation...
  9. Medicare Card: Gene Linked to Alzheimer’s Disease Plays Key Role in Cell Survival Scientists have discovered that a gene linked to Alzheimer’s disease may play a beneficial role in cell survival by enabling neurons to clear away toxic proteins. A study funded by the National Institute on Aging (NIA), part of the National Institutes of Health, shows the presenilin 1 (PS1) gene is essential to the function of […]...
  10. Medicare, NIH researchers identify genetic elements influencing the risk of type 2 diabetes Medicare, NIH researchers identify genetic elements influencing the risk of type 2 diabetes: A team led by researchers at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, has captured the most comprehensive snapshot to date of DNA regions that regulate genes in human pancreatic islet cells, a subset of […]...
  11. Researchers identify gene variant in Proteus syndrome A team of researchers has identified the genetic mutation that causes Proteus syndrome, a rare disorder in which tissue and bone grows massively out of proportion. The discovery, which has implications for potential drug therapies and even cancer, appears in the July 27, 2011, early online edition of the New England Journal of Medicine. The […]...
  12. NHGRI collaborates with Smithsonian to produce new genome exhibit To celebrate the 10th anniversary of the completion of the first complete human genome sequence — the genetic blueprint of the human body — the Smithsonian Institution will open a high-tech, high-intensity exhibit in 2013. The exhibit is a collaboration of the Smithsonian’s National Museum of Natural History (NMNH) and the National Human Genome Research […]...
  13. Sequencing program focus on inherited diseases, medical applications A new funding plan by the National Human Genome Research Institute (NHGRI) sharpens the focus of its flagship Genome Sequencing Program on medical applications. In addition to continuing on-going studies, the four-year, $416 million plan launches new efforts to find causes of rare inherited diseases and accelerate the use of genome sequence information in the […]...
  14. Medicare Card, Scientists fish for new epilepsy model and reel in potential drug Medicare Card, Scientists fish for new epilepsy model and reel in potential drug...
  15. Medicare Help, Immune Cell’s Role, Lupus Nephritis Demonstrated, Paves Way for Safety Testing, of Potential New Use for Asthma Drug National Institutes of Health scientists have discovered that the activation of immune cells called basophils causes kidney damage in a mouse model of lupus nephritis. These findings and the team’s associated research in humans may lead to new treatments for this serious disease, a severe form of systemic lupus erythematosus (SLE) that affects the kidneys […]...